pgr Phenotypes

Summary

Expression

Phenotypes

Gene Literature (12)

XB-GENEPAGE-484456

Gene Symbol: pgr Gene Name: progesterone receptor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pgr assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (47 sources): abnormal branching of the mammary ductal tree, abnormal decidualization, abnormal female reproductive system morphology, abnormal follicle stimulating hormone level, abnormal humerus morphology, abnormal lactation, abnormal mammary gland alveolus morphology, abnormal mammary gland development, abnormal mammary gland epithelium morphology, abnormal mammary gland growth during pregnancy, abnormal mammary gland physiology, abnormal mating receptivity, abnormal osteoclast morphology, abnormal ovulation, abnormal response/metabolism to endogenous compounds, abnormal sexual interaction, abnormal uterine environment, abnormal uterus development, abnormal uterus morphology, abnormal uterus physiology, abnormal vascular permeability, abnormal vascular wound healing, absent corpus luteum, anovulation, decreased circulating glucose level, decreased incidence of induced tumors, decreased mammary gland epithelial cell proliferation, dilated uterus, endocrine/exocrine gland phenotype, enlarged endometrial glands, impaired embryo implantation, impaired luteinization, improved glucose tolerance, increased bone mass, increased circulating prolactin level, increased compact bone thickness, increased insulin secretion, increased mature ovarian follicle number, increased pancreatic beta cell number, increased pancreatic beta cell proliferation, increased trabecular bone thickness, no abnormal phenotype detected, pancreatic islet hyperplasia, reproductive system phenotype, uterus hyperplasia, uterus inflammation, vascular smooth muscle hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (47 sources): abnormal branching of the mammary ductal tree, abnormal decidualization, abnormal female reproductive system morphology, abnormal follicle stimulating hormone level, abnormal humerus morphology, abnormal lactation, abnormal mammary gland alveolus morphology, abnormal mammary gland development, abnormal mammary gland epithelium morphology, abnormal mammary gland growth during pregnancy, [+]