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Summary Expression Phenotypes Gene Literature (266) GO Terms (14) Nucleotides (594) Proteins (50) Interactants (1406) Wiki

sox3     SRY-box 3

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: sox3 manipulated (1 source), sox3 assayed (32 sources)
Computed annotations: sox3 manipulated (3 sources), sox3 assayed (4 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Wt + pou5f3.2 MO + pou5f3.3 MO + sox3 MO (3 sources), Xla Wt + sox3 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (80 sources): Abnormal cardiovascular system morphology, Abnormal prolactin level, Abnormality of secondary sexual hair, Abnormality of the hypothalamus-pituitary axis, Absence of secondary sex characteristics, Absent septum pellucidum, Agenesis of corpus callosum, Ambiguous genitalia, Amenorrhea, Anosmia, [+]
Mouse (39 sources): abnormal Rathke's pouch development, abnormal Sertoli cell morphology, abnormal adenohypophysis development, abnormal brain commissure morphology, abnormal craniofacial morphology, abnormal diencephalon morphology, abnormal female reproductive system morphology, abnormal hippocampal commissure morphology, abnormal oocyte morphology, abnormal ovarian follicle morphology, [+]

View all ortholog results at Monarch