| Monarch Ortholog Phenotypes
|
Human (29 sources):
Abnormal C-peptide level,
Abnormal insulin level,
Abnormal oral glucose tolerance,
Abnormality of the genitourinary system,
Abnormality of the kidney,
Cleft palate,
Decreased waist to hip ratio,
Elevated hemoglobin A1c,
Exocrine pancreatic insufficiency,
Glucose intolerance,
Glycosuria,
Hepatocellular adenoma,
Hyperglycemia,
Hyperinsulinemic hypoglycemia,
Hypoinsulinemia,
Insulin resistance,
Insulin-resistant diabetes mellitus,
Intrauterine growth retardation,
Large for gestational age,
Maturity-onset diabetes of the young,
Neonatal hypoglycemia,
Nephropathy,
Obesity,
Overweight,
Pancreatic hypoplasia,
Renal cyst,
Retinopathy,
Transient neonatal diabetes mellitus,
Type II diabetes mellitus
[+]
|
|
Mouse (15 sources):
abnormal circulating alkaline phosphatase level,
abnormal pancreas secretion,
abnormal pancreatic islet morphology,
absent pancreatic beta cells,
absent pancreatic delta cells,
decreased body size,
endocrine/exocrine gland phenotype,
increased circulating alkaline phosphatase level,
increased pancreatic alpha cell number,
increased respiratory quotient,
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.