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Summary Expression Phenotypes Gene Literature (8) GO Terms (5) Nucleotides (75) Proteins (50) Interactants (102) Wiki

sim1     SIM bHLH transcription factor 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sim1 assayed (5 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Abnormal autonomic nervous system physiology, Attention deficit hyperactivity disorder, Autistic behavior, Cognitive impairment, Global developmental delay, Glucose intolerance, Hyperinsulinemia, Hypotension, Low levels of vitamin B1, Memory impairment, [+]
Mouse (20 sources): abnormal brown adipose tissue morphology, abnormal diencephalon morphology, abnormal energy homeostasis, abnormal nervous system tract morphology, abnormal paraventricular hypothalamic nucleus morphology, abnormal pituicyte morphology, abnormal supraoptic nucleus morphology, abnormal white adipose tissue morphology, absent magnocellular neurosecretory cells, decreased apoptosis, [+]

View all ortholog results at Monarch