|
XB-GENEPAGE-486003
smad7 SMAD family member 7
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
|
|---|
| abnormal axis elongation (1 source), abnormal gastrulation (1 source), abnormal head morphology (1 source), abnormal tail bud morphology (1 source), abnormally delayed closure of blastopore (1 source), decreased length of anterior-posterior axis (1 source), obsolete duplicated dorsal-ventral axis (1 source), wholly ventralized embryo (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
|
|---|
| Computed annotations: smad7 assayed (5 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
|
|---|
| Xtr Wt + smad7 MO (2 sources), Xla Wt + smad7 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
|
|---|
| Human (1 source): Eczematoid dermatitis |
| Mouse (38 sources): abnormal QRS complex, abnormal T-helper 1 cell differentiation, abnormal atrioventricular cushion morphology, abnormal bone marrow cell physiology, abnormal cardiovascular development, abnormal class switch recombination, abnormal fourth pharyngeal arch artery morphology, abnormal heart development, abnormal pancreatic beta cell differentiation, abnormal thymus morphology, [+] |
|
View all ortholog results at Monarch |