gdf11.1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-487192

Gene Symbol: gdf11.1 Gene Name: growth differentiation factor 11, gene 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gdf11.1 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (58 sources): abnormal cardiac stroke volume, abnormal caudal vertebrae morphology, abnormal cervical vertebrae morphology, abnormal craniofacial morphology, abnormal embryo size, abnormal exocrine pancreas morphology, abnormal hindlimb morphology, abnormal kidney development, abnormal metanephros morphology, abnormal neuron differentiation, abnormal olfactory epithelium morphology, abnormal olfactory sensory neuron morphology, abnormal palate morphology, abnormal pancreatic beta cell differentiation, abnormal rostral-caudal axis patterning, abnormal sacral vertebrae morphology, abnormal sternocostal joint morphology, abnormal stomach epithelium morphology, abnormal tail morphology, abnormal vertebral column morphology, absent amacrine cells, absent retina inner plexiform layer, absent sacral vertebrae, absent tail, absent ureter, absent ureteric bud, asymmetric rib joints, cardiovascular system phenotype, caudal body truncation, cervical vertebral transformation, decreased caudal vertebrae number, decreased pancreatic acinar cell number, decreased pancreatic beta cell mass, decreased retina photoreceptor cell number, delayed optic fissure closure, homeostasis/metabolism phenotype, impaired branching involved in ureteric bud morphogenesis, increased apoptosis, increased cardiac stroke volume, increased lumbar vertebrae number, increased neuronal precursor cell number, increased pancreatic alpha cell mass, increased pancreatic islet number, increased presacral vertebrae number, increased retina ganglion cell number, increased thoracic vertebrae number, limbs/digits/tail phenotype, lumbar vertebral transformation, muscle phenotype, neonatal lethality, complete penetrance, pancreatic islet hyperplasia, preweaning lethality, complete penetrance, respiratory system phenotype, short tail, small kidney, small pancreatic islets, thoracic vertebral transformation, vertebral transformation [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (58 sources): abnormal cardiac stroke volume, abnormal caudal vertebrae morphology, abnormal cervical vertebrae morphology, abnormal craniofacial morphology, abnormal embryo size, abnormal exocrine pancreas morphology, abnormal hindlimb morphology, abnormal kidney development, abnormal metanephros morphology, abnormal neuron differentiation, [+]