snai2 Phenotypes

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Phenotypes

Gene Literature (371)

Nucleotides (150)

Interactants (1588)

XB-GENEPAGE-487370

Gene Symbol: snai2 Gene Name: snail family transcriptional repressor 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal cell migration in neural crest (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: snai2 manipulated (5 sources), snai2 assayed (102 sources)
Computed annotations: snai2 assayed (9 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + snai2 MO (2 sources), Xla Wt + hmga2 + snai2 (1 source), Xla Wt + snai2 (1 source), Xla Wt + dnsnai2 (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (30 sources): Abnormality of calvarial morphology, Abnormality of the ear, Abnormality of the kidney, Abnormality of the pulmonary artery, Absent pigmentation of the ventral chest, Aganglionic megacolon, Ataxia, Congenital sensorineural hearing impairment, Hearing impairment, Heterochromia iridis, Hypopigmentation of hair, Hypopigmented skin patches, Hypotonia, Intellectual disability, Long philtrum, Macule, Microcephaly, Neoplasm, Neoplasm of the skin, Partial albinism, Piebald skin depigmentation, Premature graying of hair, Ptosis, Sensorineural hearing impairment, Synophrys, Telecanthus, White eyebrow, White eyelashes, White forelock, Wide nasal bridge [+]
Mouse (24 sources): abnormal T cell differentiation, abnormal cardiac epithelial to mesenchymal transition, abnormal fetal atrioventricular canal morphology, abnormal hematopoietic system morphology/development, circling, decreased atrioventricular cushion size, decreased body size, decreased forehead pigmentation, decreased hematocrit, decreased hemoglobin content, decreased litter size, diluted coat color, embryonic lethality, head blaze, hematopoietic system phenotype, immune system phenotype, increased mortality induced by gamma-irradiation, neonatal lethality, incomplete penetrance, persistence of medial edge epithelium during palatal shelf fusion, preweaning lethality, incomplete penetrance, reduced male fertility, small seminiferous tubules, small spleen, small thymus [+]
View all ortholog results at Monarch