ltbp1 Phenotypes

Phenotypes

XB-GENEPAGE-488057

Gene Symbol: ltbp1 Gene Name: latent transforming growth factor beta binding protein 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ltbp1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal ascending aorta and coronary artery attachment, abnormal cardiac neural crest cell morphology, abnormal coronary artery morphology, abnormal cranium morphology, abnormal fourth pharyngeal arch artery morphology, abnormal lower incisor morphology, abnormal snout morphology, abnormal truncus arteriosus septation, abnormal vascular smooth muscle morphology, decreased body length, decreased bone mineral content, decreased circulating alanine transaminase level, decreased circulating aspartate transaminase level, decreased circulating iron level, dilated renal tubules, increased mean corpuscular hemoglobin, integument phenotype, lethality throughout fetal growth and development, incomplete penetrance, neonatal lethality, complete penetrance, renal glomerulus cyst, short mandible, short maxilla, small basioccipital bone, small basisphenoid bone [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal ascending aorta and coronary artery attachment, abnormal cardiac neural crest cell morphology, abnormal coronary artery morphology, abnormal cranium morphology, abnormal fourth pharyngeal arch artery morphology, abnormal lower incisor morphology, abnormal snout morphology, abnormal truncus arteriosus septation, abnormal vascular smooth muscle morphology, decreased body length, [+]