efnb2 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-488605

Gene Symbol: efnb2 Gene Name: ephrin B2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: efnb2 assayed (17 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (79 sources): abnormal afferent lymphatic vessel morphology, abnormal angiogenesis, abnormal anogenital distance, abnormal anterior cardinal vein morphology, abnormal anterior commissure pars posterior morphology, abnormal axon guidance, abnormal axon morphology, abnormal cardinal vein morphology, abnormal cardiovascular development, abnormal common crus morphology, abnormal cranial neural crest cell migration, abnormal developmental vascular remodeling, abnormal dorsal-ventral polarity of the somites, abnormal endocardium morphology, abnormal endolymph, abnormal heart looping, abnormal intersomitic vessel morphology, abnormal long term depression, abnormal lymph circulation, abnormal myocardium layer morphology, abnormal neural crest cell migration, abnormal rostral-caudal patterning of the somites, abnormal second pharyngeal arch morphology, abnormal septation of the cloaca, abnormal somite development, abnormal trunk neural crest cell migration, abnormal vascular development, abnormal vestibular endolymph, abnormal vestibular endolymph ionic homeostasis, abnormal vitelline vascular remodeling, abnormal vitelline vasculature morphology, absent myocardial trabeculae, absent pharyngeal arch arteries, absent second pharyngeal arch, behavior/neurological phenotype, cardiovascular system phenotype, circling, decreased cranial neural crest cell number, decreased embryo size, decreased endolymph production, decreased posterior semicircular canal size, decreased superior semicircular canal size, digestive/alimentary phenotype, dilated endolymphatic duct, dilated endolymphatic sac, distended pericardium, embryo phenotype, embryonic growth arrest, embryonic growth retardation, embryonic lethality between implantation and placentation, incomplete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, enlarged aortic valve, enlarged pericardium, enlarged pulmonary valve, flaky skin, head bobbing, immune system phenotype, increased cranial neural crest cell apoptosis, integument phenotype, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, complete penetrance, premature death, reduced long term potentiation, reproductive system phenotype, retarded hair growth, small endolymphatic duct, small first pharyngeal arch, small hair follicles, small pharyngeal arch, small second pharyngeal arch, small trigeminal ganglion, splayed clitoris, thick aortic valve, thick mitral valve cusps, thick pulmonary valve, thin hypodermis [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (79 sources): abnormal afferent lymphatic vessel morphology, abnormal angiogenesis, abnormal anogenital distance, abnormal anterior cardinal vein morphology, abnormal anterior commissure pars posterior morphology, abnormal axon guidance, abnormal axon morphology, abnormal cardinal vein morphology, abnormal cardiovascular development, abnormal common crus morphology, [+]