mbd4 Phenotypes

Phenotypes

XB-GENEPAGE-489214

Gene Symbol: mbd4 Gene Name: methyl-CpG binding domain 4, DNA glycosylase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mbd4 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (22 sources): abnormal DNA methylation, abnormal abdominal wall morphology, abnormal cell cycle checkpoint function, abnormal cell morphology, abnormal direction of heart looping, abnormal eye development, abnormal left-right axis patterning, abnormal limb development, abnormal pharyngeal arch development, abnormal spinal cord interneuron morphology, absent embryonic cilia, decreased embryonic cilium length, decreased physiological sensitivity to xenobiotic, decreased sensitivity to induced cell death, delayed embryo turning, delayed limb development, embryonic lethality during organogenesis, complete penetrance, increased motor neuron number, open neural tube, polysyndactyly, right-sided stomach, situs inversus [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (22 sources): abnormal DNA methylation, abnormal abdominal wall morphology, abnormal cell cycle checkpoint function, abnormal cell morphology, abnormal direction of heart looping, abnormal eye development, abnormal left-right axis patterning, abnormal limb development, abnormal pharyngeal arch development, abnormal spinal cord interneuron morphology, [+]