il21r Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (36)

Interactants (1)

XB-GENEPAGE-490255

Gene Symbol: il21r Gene Name: interleukin 21 receptor

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (12 sources): Bronchiectasis, Cholangitis, Chronic diarrhea, Chronic hepatitis due to cryptosporidium infection, Cirrhosis, Failure to thrive, Hepatic failure, Immunodeficiency, Pneumonia, Recurrent infections, Recurrent respiratory infections, Recurrent sinusitis [+]
Mouse (36 sources): abnormal CD4-positive T cell differentiation, abnormal CD8-positive, alpha-beta T cell physiology, abnormal Langerhans cell physiology, abnormal T cell activation, abnormal T-helper 1 physiology, abnormal T-helper 2 physiology, abnormal dendritic cell physiology, abnormal kidney morphology, abnormal leukocyte physiology, abnormal lymphocyte physiology, abnormal memory T cell physiology, abnormal plasmacytoid dendritic cell physiology, abnormal susceptibility to infection, abnormal thymocyte activation, decreased CD4-positive, alpha beta T cell number, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased IgG3 level, decreased T cell proliferation, decreased cytotoxic T cell cytolysis, decreased eosinophil cell number, decreased granulocyte number, decreased interferon-gamma secretion, decreased interleukin-13 secretion, decreased interleukin-17 secretion, decreased interleukin-21 secretion, decreased interleukin-4 secretion, decreased susceptibility to autoimmune diabetes, decreased susceptibility to type IV hypersensitivity reaction, granulomatous inflammation, immune system phenotype, impaired eosinophil recruitment, impaired natural killer cell mediated cytotoxicity, increased interferon-gamma secretion, increased susceptibility to experimental autoimmune encephalomyelitis [+]
View all ortholog results at Monarch