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Summary Expression Phenotypes Gene Literature (38) GO Terms (3) Nucleotides (115) Proteins (58) Interactants (279) Wiki

rbpj     recombination signal binding protein for immunoglobulin kappa J region

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of hypochord (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: rbpj manipulated (13 sources)
Computed annotations: rbpj manipulated (6 sources), rbpj assayed (4 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + dnrbpj (8 sources), Xla Wt + DNrbpj + DNmcidas - animal cap explant (3 sources), Xla Wt + DNrbpj - animal cap explant (3 sources), Xla Wt + carbpj-notch1del-GR (3 sources), Xla Wt + ptf1a + rbpj (1 source), Xla Wt + dnrbpj (1 source), Xla Wt + dnrbpj (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (53 sources): 2-3 toe syndactyly, Abnormal pulmonary valve morphology, Abnormality of the lower limb, Abnormality of the metacarpal bones, Abnormality of the upper limb, Absent fingernail, Absent hand, Aplasia cutis congenita, Aplasia of the fingers, Aplasia/Hypoplasia of the skin, [+]
Mouse (105 sources): abnormal CD4-positive helper T cell morphology, abnormal T-helper 2 cell differentiation, abnormal anterior cardinal vein morphology, abnormal aortic valve morphology, abnormal atrioventricular cushion morphology, abnormal bone mineralization, abnormal cardiac epithelial to mesenchymal transition, abnormal cell differentiation, abnormal common cardinal vein morphology, abnormal crypts of Lieberkuhn morphology, [+]

View all ortholog results at Monarch