pdk4 Phenotypes

Phenotypes

XB-GENEPAGE-491644

Gene Symbol: pdk4 Gene Name: pyruvate dehydrogenase kinase 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: pdk4 assayed (1 source)
Computed annotations: pdk4 assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (13 sources): abnormal blood homeostasis, abnormal bone volume, abnormal glycerol level, abnormal osteoclast cell number, abnormal osteoclast differentiation, abnormal osteoclast morphology, abnormal trabecular bone thickness, abnormal trabecular bone volume, decreased circulating glucose level, decreased circulating lactate level, decreased liver glycogen level, improved glucose tolerance, increased circulating ketone body level [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (13 sources): abnormal blood homeostasis, abnormal bone volume, abnormal glycerol level, abnormal osteoclast cell number, abnormal osteoclast differentiation, abnormal osteoclast morphology, abnormal trabecular bone thickness, abnormal trabecular bone volume, decreased circulating glucose level, decreased circulating lactate level, [+]