| Monarch Ortholog Phenotypes
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Human (20 sources):
Akinesia,
Arachnodactyly,
Areflexia,
Camptodactyly,
Decreased fetal movement,
Dementia,
Dolichocephaly,
Fetal akinesia sequence,
High palate,
High, narrow palate,
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Mouse (25 sources):
abnormal Purkinje cell morphology,
abnormal axon fasciculation,
abnormal axon guidance,
abnormal cerebellar Golgi cell morphology,
abnormal cerebellar granule cell morphology,
abnormal cerebellar granule layer morphology,
abnormal cerebellar molecular layer,
abnormal dendrite morphology,
abnormal limb posture,
abnormal motor capabilities/coordination/movement,
behavior/neurological phenotype,
circling,
decreased body size,
impaired limb coordination,
lethality at weaning, complete penetrance,
muscle phenotype,
nervous system phenotype,
postnatal lethality, complete penetrance,
prenatal lethality, incomplete penetrance,
preweaning lethality, complete penetrance,
preweaning lethality, incomplete penetrance,
small cerebellum,
stomach non-glandular epithelium hyperkeratosis,
vision/eye phenotype,
weakness
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.