| Monarch Ortholog Phenotypes
|
|
Human (14 sources):
Abnormal pyramidal sign,
Cerebellar atrophy,
Difficulty walking,
Dysarthria,
Dysphagia,
Dystonia,
Gait imbalance,
Horizontal nystagmus,
Hyperreflexia,
Jerky ocular pursuit movements,
[+]
|
Mouse (21 sources):
abnormal brain development,
abnormal cell morphology,
abnormal cranial flexure morphology,
abnormal direction of heart looping,
abnormal embryo size,
abnormal embryo turning,
abnormal embryonic tissue morphology,
abnormal limb development,
abnormal nervous system development,
abnormal pericardium morphology,
abnormal somite shape,
abnormal tail bud morphology,
absent embryonic cilia,
decreased embryo size,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
incomplete embryo turning,
nervous system phenotype,
perinatal lethality, complete penetrance,
prenatal lethality, incomplete penetrance,
preweaning lethality, complete penetrance
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.