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Summary Expression Phenotypes Gene Literature (15) GO Terms (9) Nucleotides (338) Proteins (72) Interactants (305) Wiki

wdr5     WD repeat domain 5

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of anterior-posterior axis (3 sources), abnormal development of dorsal-ventral axis (3 sources), wholly ventralized embryo (3 sources), abnormal tail morphology (1 source), absent blood in the heart (1 source), absent heart (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the head (1 source), decreased size of the tail (1 source), partially ventralized embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: wdr5 manipulated (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + wdr5 mKD (4 sources), Xla Wt + wdr5 MO (2 sources), Xla Wt + wdr5 mKD (1 source)