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Summary Expression Phenotypes Gene Literature (1) GO Terms (10) Nucleotides (119) Proteins (51) Interactants (63) Wiki
XB-GENEPAGE-493987

alox5     arachidonate 5-lipoxygenase

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: alox5 assayed (1 source)
Computed annotations: alox5 assayed (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (12 sources): abnormal thromboxane level, cardiovascular system phenotype, decreased acute inflammation, decreased leukotriene level, decreased susceptibility to experimental autoimmune uveoretinitis, decreased susceptibility to type I hypersensitivity reaction, hematopoietic system phenotype, immune system phenotype, impaired neutrophil recruitment, increased prostaglandin level, [+]