| Monarch Ortholog Phenotypes
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Human (8 sources):
Anemia,
Edema,
Focal segmental glomerulosclerosis,
Hyperlipidemia,
Hypertension,
Hypoalbuminemia,
Proteinuria,
Stage 5 chronic kidney disease
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Mouse (46 sources):
abnormal Mullerian duct morphology,
abnormal atrioventricular cushion morphology,
abnormal blood urea nitrogen level,
abnormal coronary sinus connection,
abnormal ductus venosus valve morphology,
abnormal ductus venosus valve topology,
abnormal eye muscle morphology,
abnormal glomerular capillary morphology,
abnormal hypoglossal canal morphology,
abnormal hypoglossal nerve topology,
abnormal infrahyoid muscle connection,
abnormal intestine placement,
abnormal lens epithelium morphology,
abnormal lymphocyte chemotaxis,
abnormal optic cup morphology,
abnormal podocyte adhesion,
abnormal podocyte morphology,
abnormal renal glomerulus basement membrane morphology,
abnormal renal glomerulus morphology,
absent ductus venosus valve,
absent hypoglossal canal,
absent hypoglossal nerve,
absent stapedial artery,
absent superior cervical ganglion,
blood in lymph vessels,
cortical renal glomerulopathies,
decreased podocyte number,
detached podocyte,
dilated liver sinusoidal spaces,
dilated renal tubules,
embryo tumor,
heterochrony,
increased trigeminal neuroma incidence,
multiple persisting craniopharyngeal ducts,
pale kidney,
perinatal lethality, incomplete penetrance,
persistent dorsal ophthalmic artery,
podocyte foot process effacement,
premature death,
preweaning lethality, incomplete penetrance,
renal cast,
small hypoglossal canal,
small kidney,
small superior cervical ganglion,
subcutaneous edema,
thin hypoglossal nerve
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.