| Monarch Ortholog Phenotypes
|
Human (27 sources):
Abnormality of extrapyramidal motor function,
Decreased number of peripheral myelinated nerve fibers,
Delayed gross motor development,
Difficulty walking,
Distal amyotrophy,
Distal lower limb amyotrophy,
Dysarthria,
Exaggerated startle response,
Flexion contracture,
Hyperhidrosis,
Hyporeflexia,
Hyporeflexia of lower limbs,
Impaired vibration sensation in the lower limbs,
Kyphosis,
Motor axonal neuropathy,
Motor delay,
Multiple joint contractures,
Nystagmus,
Optic atrophy,
Optic disc pallor,
Peripheral axonal neuropathy,
Pes cavus,
Progressive spastic paraplegia,
Proximal hyperreflexia,
Scoliosis,
Sensory axonal neuropathy,
Spastic paraplegia
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Mouse (1 source):
no abnormal phenotype detected
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.