Monarch Ortholog Phenotypes
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Mouse (20 sources):
abnormal pain threshold,
abnormal physiological response to xenobiotic,
abnormal systemic arterial blood pressure,
abnormal thermal nociception,
cardiovascular system phenotype,
decreased circulating interleukin-18 level,
decreased dendritic cell number,
decreased physiological sensitivity to xenobiotic,
decreased susceptibility to endotoxin shock,
decreased susceptibility to induced arthritis,
decreased susceptibility to injury,
decreased susceptibility to type IV hypersensitivity reaction,
immune system phenotype,
impaired leukocyte tethering or rolling,
improved glucose tolerance,
increased cerebral infarct size,
increased startle reflex,
increased susceptibility to induced pancreatitis,
perinatal lethality, incomplete penetrance,
postnatal lethality, incomplete penetrance
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