cth Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (5)

Nucleotides (421)

Interactants (423)

XB-GENEPAGE-5784448

Gene Symbol: cth Gene Name: cystathionine gamma-lyase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cth assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (8 sources): Cystathioninemia, Cystathioninuria, Intellectual disability, Nephrolithiasis, Seizure, Talipes equinovarus, Tremor, obsolete External ear malformation
Mouse (19 sources): cardiovascular system phenotype, decreased circulating cysteine level, decreased glutathione level, decreased lactate dehydrogenase level, decreased locomotor activity, decreased physiological sensitivity to xenobiotic, decreased skeletal muscle fiber diameter, decreased vasodilation, increased cellular sensitivity to oxidative stress, increased circulating alanine transaminase level, increased circulating alkaline phosphatase level, increased circulating aspartate transaminase level, increased circulating homocysteine level, increased physiological sensitivity to xenobiotic, increased sensitivity to induced cell death, increased sensitivity to induced morbidity/mortality, increased susceptibility to induced muscular atrophy, increased susceptibility to weight loss, renal/urinary system phenotype [+]
View all ortholog results at Monarch