| Monarch Ortholog Phenotypes
|
Human (22 sources):
Abnormal pyramidal sign,
Abnormal upper motor neuron morphology,
Abnormality of the bladder,
Amyotrophic lateral sclerosis,
Babinski sign,
Decreased motor nerve conduction velocity,
Decreased muscle mass,
Distal amyotrophy,
Distal muscle weakness,
Dysarthria,
EMG abnormality,
Foot dorsiflexor weakness,
Gait disturbance,
Hammertoe,
Hyperreflexia,
Hyporeflexia,
Pes cavus,
Pseudobulbar affect,
Sensory neuropathy,
Spasticity,
Spinal muscular atrophy,
Split hand
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|
Mouse (3 sources):
behavior/neurological phenotype,
behavioral despair,
decreased locomotor activity
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.