| Monarch Ortholog Phenotypes
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Human (25 sources):
Abnormality of eye movement,
Autism,
Brachycephaly,
Brachydactyly,
Broad forehead,
Craniosynostosis,
Facial asymmetry,
Frontal bossing,
Global developmental delay,
Hallux valgus,
Hearing impairment,
Hypertelorism,
Increased intracranial pressure,
Intellectual disability,
Low anterior hairline,
Macrocephaly,
Metacarpal synostosis,
Midface retrusion,
Plagiocephaly,
Proptosis,
Ptosis,
Single transverse palmar crease,
Strabismus,
Underdeveloped supraorbital ridges,
Visual field defect
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|
Mouse (17 sources):
abnormal response to transplant,
abnormal T cell differentiation,
absent T cells,
arrested T cell differentiation,
decreased CD4-positive, alpha beta T cell number,
decreased double-positive T cell number,
decreased immature B cell number,
decreased pre-B cell number,
decreased pro-B cell number,
decreased thymocyte number,
hematopoietic system phenotype,
increased CD8-positive, alpha-beta T cell number,
increased double-negative T cell number,
increased effector memory CD4-positive, alpha-beta T cell number,
nervous system phenotype,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.