rapgef2 Phenotypes

Phenotypes

XB-GENEPAGE-5814344

Gene Symbol: rapgef2 Gene Name: Rap guanine nucleotide exchange factor 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: rapgef2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (34 sources): abnormal brain development, abnormal cell adhesion, abnormal cell migration, abnormal definitive hematopoiesis, abnormal digestive system development, abnormal embryonic hematopoiesis, abnormal erythropoiesis, abnormal heart development, abnormal hematopoietic stem cell physiology, abnormal liver development, abnormal vascular development, abnormal vasculogenesis, abnormal visceral yolk sac blood island morphology, absent erythrocytes, absent vitelline blood vessels, decreased birth body size, decreased cell proliferation, decreased common myeloid progenitor cell number, decreased embryo size, decreased erythrocyte cell number, decreased hematopoietic stem cell number, delayed embryo turning, embryonic growth arrest, embryonic lethality during organogenesis, complete penetrance, embryonic lethality prior to tooth bud stage, enlarged allantois, hematopoietic system phenotype, immune system phenotype, incomplete embryo turning, lethality throughout fetal growth and development, incomplete penetrance, pale liver, pale yolk sac, preweaning lethality, complete penetrance, wavy neural tube [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (34 sources): abnormal brain development, abnormal cell adhesion, abnormal cell migration, abnormal definitive hematopoiesis, abnormal digestive system development, abnormal embryonic hematopoiesis, abnormal erythropoiesis, abnormal heart development, abnormal hematopoietic stem cell physiology, abnormal liver development, [+]