cdk4 Phenotypes

Phenotypes

XB-GENEPAGE-5900654

Gene Symbol: cdk4 Gene Name: cyclin-dependent kinase 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdk4 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (30 sources): abnormal Sertoli cell morphology, abnormal body length, abnormal corpus luteum morphology, abnormal cranium morphology, abnormal embryo size, abnormal female reproductive system morphology, abnormal fertility/fecundity, abnormal locomotor behavior, abnormal pancreatic islet morphology, abnormal seminiferous tubule morphology, absent Leydig cells, decreased Leydig cell number, decreased body length, decreased body size, decreased circulating progesterone level, decreased lactotroph cell number, decreased testis weight, delayed estrous cycle, homeostasis/metabolism phenotype, impaired limb coordination, impaired luteinization, increased pancreatic beta cell number, no abnormal phenotype detected, postnatal lethality, postnatal lethality, incomplete penetrance, preweaning lethality, incomplete penetrance, reduced male fertility, small ovary, small pancreatic islets, small seminiferous tubules [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (30 sources): abnormal Sertoli cell morphology, abnormal body length, abnormal corpus luteum morphology, abnormal cranium morphology, abnormal embryo size, abnormal female reproductive system morphology, abnormal fertility/fecundity, abnormal locomotor behavior, abnormal pancreatic islet morphology, abnormal seminiferous tubule morphology, [+]