| Monarch Ortholog Phenotypes
|
Human (28 sources):
Abnormal cardiac septum morphology,
Anemia,
Astigmatism,
Autistic behavior,
Broad-based gait,
Clinodactyly of the 5th finger,
Coarse facial features,
Cryptorchidism,
Delayed ability to walk,
Delayed speech and language development,
Downslanted palpebral fissures,
Downturned corners of mouth,
Enlarged cisterna magna,
Epileptic encephalopathy,
Generalized hypotonia,
Global developmental delay,
Hypermetropia,
Hypertelorism,
Intellectual disability,
Myopia,
Neutropenia,
Nystagmus,
Seizure,
Strabismus,
Synophrys,
Thin upper lip vermilion,
Wide mouth,
Wide nasal bridge
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Mouse (4 sources):
abnormal response/metabolism to endogenous compounds,
decreased apoptosis,
decreased grip strength,
increased startle reflex
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.