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XB-GENEPAGE-5933084
nup188 nucleoporin 188kDa
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal heart looping (5 sources), abnormally decreased number of cilium in the left-right organizer (5 sources), abnormal heart morphology (3 sources), abnormal multiciliated cell (2 sources), abnormally decreased number of cilium in the multiciliated epidermal cell (2 sources), abnormally localised basal body (2 sources) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: nup188 manipulated (5 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| congenital heart disease (12AP sources, 5 EP sources), visceral heterotaxy (12AP sources, 5 EP sources), ciliopathy (2AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr Wt + nup188 MO (4 sources), Xtr Wt + nup188 MO (4 sources), Xtr Wt + nup188 MO (3 sources), Xtr Wt + nup188 (2 sources), Xtr Wt + nup188 (2 sources), Xtr Wt + Hsa.NUP188 (1 source), Xtr wt + nup188 MO (1 source), Xtr Wt + nup188 MO (1 source), Xtr wt + nup188 MO + nup205 MO (1 source) |