myh10 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-5957387

Gene Symbol: myh10 Gene Name: myosin, heavy chain 10, non-muscle

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal mitotic cell (2 sources), abnormally localised mitotic spindle in epithelial cell (2 sources), abnormal actin cytoskeleton (1 source), abnormal animal cap morphology (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + myh10 MO (3 sources), Xla Wt + Hsa.krasV12 : GFP + myh10 MO (2 sources), Xla Wt + myh10 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (66 sources): abnormal Purkinje cell dendrite morphology, abnormal Purkinje cell morphology, abnormal aortic valve morphology, abnormal atrial thrombosis, abnormal body size, abnormal cerebellar Purkinje cell layer, abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cerebellar molecular layer, abnormal cerebellum development, abnormal cerebellum external granule cell layer morphology, abnormal cerebral aqueduct morphology, abnormal cerebral cortex morphology, abnormal cranium morphology, abnormal embryo size, abnormal fetal cardiomyocyte morphology, abnormal fourth ventricle morphology, abnormal heart apex morphology, abnormal heart shape, abnormal impulse conducting system conduction, abnormal intercalated disk morphology, abnormal locomotor behavior, abnormal myocardial fiber morphology, abnormal myocardial fiber physiology, abnormal myocardium compact layer morphology, abnormal pericardium morphology, abnormal retina bipolar cell morphology, abnormal skin coloration, abnormal spinal cord central canal morphology, abnormal suckling behavior, abnormal ventricle myocardium morphology, absent coronary vessels, atrioventricular septal defect, cardiac hypertrophy, cardiac interstitial fibrosis, cardiovascular system phenotype, decreased cardiac muscle contractility, decreased survivor rate, domed cranium, double outlet right ventricle with atrioventricular septal defect, ectopic Purkinje cell, embryonic lethality, complete penetrance, enlarged lateral ventricles, enlarged myocardial fiber, heart hemorrhage, heart inflammation, heart right ventricle outflow tract stenosis, impaired balance, improved glucose tolerance, increased cardiomyocyte apoptosis, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, myocardial trabeculae hypoplasia, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, prenatal lethality prior to heart atrial septation, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, small cerebellum, thin cerebral cortex, thin interventricular septum, thin ventricular wall, ventricular hypoplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (66 sources): abnormal Purkinje cell dendrite morphology, abnormal Purkinje cell morphology, abnormal aortic valve morphology, abnormal atrial thrombosis, abnormal body size, abnormal cerebellar Purkinje cell layer, abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cerebellar molecular layer, abnormal cerebellum development, [+]