| Monarch Ortholog Phenotypes
|
Human (52 sources):
Abnormal blistering of the skin,
Abnormal dental enamel morphology,
Abnormal rib morphology,
Abnormal skull morphology,
Abnormal toenail morphology,
Abnormality of skin pigmentation,
Abnormality of the anus,
Acral blistering,
Amniotic constriction ring,
Anemia,
Aplasia/Hypoplasia of the skin,
Atypical scarring of skin,
Camptodactyly of finger,
Carious teeth,
Cheilitis,
Colitis,
Conjunctivitis,
Corneal erosion,
Corneal opacity,
Cutaneous photosensitivity,
Dermal atrophy,
Diffuse skin atrophy,
Dysphagia,
Ectropion,
Erythema,
Esophageal stricture,
Finger syndactyly,
Flexion contracture,
Fragile skin,
Gingivitis,
Hyperkeratosis,
Inflammation of the large intestine,
Laryngeal stenosis,
Milia,
Neoplasm of the urethra,
Palmoplantar hyperkeratosis,
Palmoplantar keratoderma,
Periodontitis,
Phimosis,
Poikiloderma,
Premature loss of primary teeth,
Recurrent skin infections,
Ridged nail,
Short 4th metacarpal,
Short 5th metacarpal,
Spotty hyperpigmentation,
Spotty hypopigmentation,
Squamous cell carcinoma,
Symblepharon,
Turricephaly,
Urethral stricture,
obsolete Telangiectases in sun-exposed and nonexposed skin
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Mouse (11 sources):
abnormal colon morphology,
decreased keratinocyte adhesion,
decreased keratinocyte proliferation,
distended ileum,
distended stomach,
ileum inflammation,
increased urine osmolality,
postnatal lethality, complete penetrance,
renal/urinary system phenotype,
skin atrophy,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.