abnormal neuronal precursor proliferation, abnormal physiological response to xenobiotic, abnormal skeleton physiology, abnormal telencephalon development, abnormal telencephalon morphology, abnormal white adipose tissue physiology, adipose tissue phenotype, decreased bone strength, decreased carbon dioxide production, decreased energy expenditure, decreased heart weight, decreased lean body mass, decreased oxygen consumption, decreased susceptibility to hepatic steatosis, decreased white fat cell size, hindlimb paresis, increased bone trabecula number, increased circulating glucose level, increased epididymal fat pad weight, increased insulin sensitivity, increased lean body mass, increased osteoclast cell number, increased percent body fat/body weight, increased prepulse inhibition, increased startle reflex, increased susceptibility to diet-induced obesity, increased trabecular bone volume, increased white adipose tissue amount, increased white fat cell number, lethality throughout fetal growth and development, complete penetrance, liver/biliary system phenotype, nervous system phenotype, osteosclerosis, palatal shelves fail to meet at midline, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, thin cortical plate, thin ventricular wall