| Monarch Ortholog Phenotypes
|
Human (25 sources):
Abnormal electroretinogram,
Abnormality of retinal pigmentation,
Achromatopsia,
Attenuation of retinal blood vessels,
Blue cone monochromacy,
Bull's eye maculopathy,
Cataract,
Central scotoma,
Color vision defect,
Dyschromatopsia,
Exotropia,
Granular macular appearance,
High myopia,
Horizontal pendular nystagmus,
Hypermetropia,
Hypoplasia of the fovea,
Macular degeneration,
Monochromacy,
Pendular nystagmus,
Photophobia,
Retinal pigment epithelial atrophy,
Retinitis pigmentosa inversa,
Severely reduced visual acuity,
Varicose veins,
Visual impairment
[+]
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Mouse (6 sources):
abnormal cone electrophysiology,
abnormal retina cone cell outer segment morphology,
decreased retina cone cell number,
disorganized photoreceptor outer segment,
increased retina apoptosis,
retina cone cell degeneration
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.