| Monarch Ortholog Phenotypes
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Human (15 sources):
Abnormal bleeding,
Abnormality of the menstrual cycle,
Abnormality of thrombocytes,
Bruising susceptibility,
Epistaxis,
Impaired collagen-induced platelet aggregation,
Impaired thrombin-induced platelet aggregation,
Menorrhagia,
Myelodysplasia,
Myelofibrosis,
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Mouse (12 sources):
abnormal megakaryocyte differentiation,
abnormal megakaryocyte morphology,
abnormal platelet activation,
abnormal response to injury,
decreased bone mineral content,
decreased cerebral infarct size,
decreased metastatic potential,
decreased platelet alpha-granule number,
decreased susceptibility to induced thrombosis,
enhanced megakaryocyte emperipolesis,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.