Monarch Ortholog Phenotypes
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Mouse (27 sources):
abnormal bone marrow cell number,
abnormal mitochondrial physiology,
abnormal skeletal muscle morphology,
abnormal splenocyte morphology,
absent B-2 B cells,
arrested B cell differentiation,
cardiac hypertrophy,
cardiovascular system phenotype,
decreased B-1 B cell number,
decreased IgG1 level,
decreased IgG2a level,
decreased marginal zone B cell number,
decreased mature B cell number,
decreased pre-B cell number,
decreased transitional stage B cell number,
enhanced autophagy,
impaired hematopoiesis,
increased B cell apoptosis,
increased B-1 B cell number,
increased CD4-positive, alpha beta T cell number,
increased cardiac muscle glycogen level,
increased pro-B cell number,
increased single-positive T cell number,
premature death,
prolonged QRS complex duration,
renal/urinary system phenotype,
small spleen
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