| Monarch Ortholog Phenotypes
|
Human (22 sources):
Ankle clonus,
Babinski sign,
Broad-based gait,
Cerebellar hypoplasia,
Cerebral dysmyelination,
Dysmetria,
Esotropia,
Exotropia,
Frontal polymicrogyria,
Global developmental delay,
Hyperreflexia,
Hypoplasia of the brainstem,
Hypoplasia of the pons,
Intellectual disability,
Language impairment,
Nystagmus,
Perisylvian polymicrogyria,
Seizure,
Spasticity,
Truncal ataxia,
Ventriculomegaly,
obsolete Frontoparietal polymicrogyria
[+]
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Mouse (19 sources):
abnormal Cajal-Retzius cell morphology,
abnormal Sertoli cell morphology,
abnormal astrocyte morphology,
abnormal basement membrane morphology,
abnormal cerebellar cortex morphology,
abnormal cerebellar granule cell migration,
abnormal cerebellum lobule morphology,
abnormal cerebral cortex morphology,
abnormal locomotor behavior,
abnormal pontine nuclei morphology,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.