htra2 Phenotypes

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Phenotypes

Gene Literature (2)

Nucleotides (79)

Interactants (100)

XB-GENEPAGE-6044195

Gene Symbol: htra2 Gene Name: HtrA serine peptidase 2

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (21 sources): 3-Methylglutaconic aciduria, Apnea, Bradycardia, Cataract, Cerebral atrophy, Dystonia, Feeding difficulties, Generalized hypotonia, Growth delay, Hypoplasia of the corpus callosum, Increased CSF lactate, Increased circulating lactate concentration, Neutropenia, Poor suck, Respiratory insufficiency, Secondary microcephaly, Seizure, Sensorineural hearing impairment, Spasticity, Tremor, Ventriculomegaly [+]
Mouse (39 sources): abnormal action potential, abnormal astrocyte morphology, abnormal basal ganglion morphology, abnormal bone marrow cell morphology/development, abnormal cerebellar granule cell morphology, abnormal interleukin level, abnormal locomotor behavior, abnormal mitochondrial crista morphology, abnormal mitochondrial inner membrane morphology, abnormal respiratory electron transport chain, abnormal seminal vesicle morphology, abnormal thymus morphology, abnormal tumor necrosis factor level, decreased body size, decreased brain size, decreased brain weight, decreased double-positive T cell number, decreased grip strength, decreased locomotor activity, decreased pre-B cell number, decreased pro-B cell number, decreased single-positive T cell number, dilated mitochondria, hunched posture, impaired balance, increased apoptosis, increased brain apoptosis, increased susceptibility to neuronal excitotoxicity, limb grasping, loss of basal ganglia neurons, muscular atrophy, nervous system phenotype, no spontaneous movement, premature death, small heart, small spleen, small thymus, spleen atrophy, thymus atrophy [+]
View all ortholog results at Monarch