| Monarch Ortholog Phenotypes
|
Human (44 sources):
Abnormality of extrapyramidal motor function,
Agitation,
Ataxia,
Axial hypotonia,
Bradykinesia,
Chorea,
Choreoathetosis,
Clonus,
Delayed speech and language development,
Depression,
Drowsiness,
Dysphagia,
Dystonia,
Excessive daytime somnolence,
Excessive salivation,
Falls,
Global developmental delay,
Hyperkinetic movements,
Hyperphenylalaninemia,
Hyperreflexia,
Hypotonia,
Hypsarrhythmia,
Intellectual disability,
Intellectual disability, progressive,
Irritability,
Microcephaly,
Motor delay,
Myoclonus,
Oculogyric crisis,
Opisthotonus,
Pallor,
Parkinsonism,
Poor head control,
Poor suck,
Progressive neurologic deterioration,
Psychomotor retardation,
Ptosis,
Recurrent fever,
Restlessness,
Rigidity,
Seizure,
Small for gestational age,
Spasticity,
Tremor
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Mouse (16 sources):
abnormal dopamine level,
abnormal serotonin level,
abnormal sexual maturation,
decreased dopamine level,
decreased locomotor activity,
decreased noradrenaline level,
decreased serotonin level,
diluted coat color,
increased phenylalanine level,
increased salivation,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.