gmnc Phenotypes

Phenotypes

XB-GENEPAGE-6048920

Gene Symbol: gmnc Gene Name: geminin coiled-coil domain containing

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of embryo (1 source), abnormal development of multiciliated epidermal cell (1 source), abnormally decreased number of ciliated cell (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: gmnc manipulated (4 sources)
Computed annotations: gmnc assayed (17 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + gmnc MO (3 sources), Xla Wt + Hsa.gmnc (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (21 sources): abnormal grip strength, abnormal motile cilium morphology, abnormal nasal mucosa goblet cell morphology, abnormal seminiferous tubule morphology, abnormal spermatid morphology, abnormal tracheal ciliated epithelium morphology, absent brain ependyma motile cilia, absent oviduct epithelium motile cilium, absent respiratory motile cilia, decreased primordial ovarian follicle number, decreased survivor rate, decreased tertiary ovarian follicle number, hippocampus atrophy, increased cell death, increased grip strength, increased respiratory mucosa goblet cell number, ovary degeneration, postnatal lethality, complete penetrance, slow postnatal weight gain, small ovary, small oviduct [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (21 sources): abnormal grip strength, abnormal motile cilium morphology, abnormal nasal mucosa goblet cell morphology, abnormal seminiferous tubule morphology, abnormal spermatid morphology, abnormal tracheal ciliated epithelium morphology, absent brain ependyma motile cilia, absent oviduct epithelium motile cilium, absent respiratory motile cilia, decreased primordial ovarian follicle number, [+]