gnai2 Phenotypes

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Phenotypes

Gene Literature (15)

Nucleotides (203)

Interactants (160)

XB-GENEPAGE-6050843

Gene Symbol: gnai2 Gene Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (4 sources): Abnormality of metabolism/homeostasis, Paroxysmal ventricular tachycardia, Right bundle branch block, Sudden cardiac death
Mouse (36 sources): abnormal cellular extravasation, abnormal colon morphology, abnormal cytokine level, abnormal eosinophil physiology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal leukocyte adhesion, abnormal response/metabolism to endogenous compounds, cardiovascular system phenotype, decreased T-helper 17 cell number, decreased eosinophil cell number, decreased physiological sensitivity to xenobiotic, immune system phenotype, increased T cell proliferation, increased circulating interferon-gamma level, increased circulating interleukin-4 level, increased circulating interleukin-5 level, increased granulocyte number, increased incidence of tumors by chemical induction, increased interferon-gamma secretion, increased interleukin-1 beta secretion, increased interleukin-2 secretion, increased neutrophil cell number, increased physiological sensitivity to xenobiotic, increased sensitivity to xenobiotic induced morbidity/mortality, increased single-positive T cell number, increased susceptibility to induced colitis, increased susceptibility to parasitic infection, increased thymocyte number, increased tumor necrosis factor secretion, intestinal ulcer, lethality during fetal growth through weaning, complete penetrance, megacolon, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, premature death [+]
View all ortholog results at Monarch