Monarch Ortholog Phenotypes
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Human (1 source):
Eczematoid dermatitis
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Mouse (52 sources):
abnormal chondrocyte differentiation,
abnormal chondrocyte morphology,
abnormal lung vasculature morphology,
abnormal osteoblast morphology,
abnormal osteoblast physiology,
abnormal osteoclast differentiation,
abnormal osteoclast morphology,
abnormal osteoclast physiology,
abnormal skeleton development,
abnormal vertebrae development,
abnormal vertebral arch morphology,
adipose tissue phenotype,
cardiac fibrosis,
decreased body size,
decreased bone mineralization,
decreased bone ossification,
decreased bone trabecula number,
decreased bone volume,
decreased circulating adiponectin level,
decreased circulating glucose level,
decreased circulating osteocalcin level,
decreased gonadal fat pad weight,
decreased insulin secretion,
decreased liver triglyceride level,
decreased susceptibility to hepatic steatosis,
decreased trabecular bone thickness,
decreased width of hypertrophic chondrocyte zone,
delayed endochondral bone ossification,
esophagus fibrosis,
homeostasis/metabolism phenotype,
hunched posture,
hypoxia,
improved glucose tolerance,
increased bone mass,
increased bone ossification,
increased bone trabecula number,
increased bone volume,
increased circulating osteocalcin level,
increased fibrosarcoma incidence,
increased gonadal fat pad weight,
increased insulin sensitivity,
increased lung weight,
increased osteoclast cell number,
increased trabecular bone thickness,
postnatal lethality, complete penetrance,
premature death,
renal/urinary system phenotype,
skeleton phenotype,
skin fibrosis,
stomach fibrosis,
thymus fibrosis,
vascular smooth muscle hyperplasia
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View all ortholog results at Monarch
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