| Monarch Ortholog Phenotypes
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Human (22 sources):
Abnormality of endocrine pancreas physiology,
Abnormality of iron homeostasis,
Anemia,
Arthropathy,
Cardiomyopathy,
Cirrhosis,
Congenital hepatic fibrosis,
Congestive heart failure,
Diabetes mellitus,
Dilated cardiomyopathy,
Elevated circulating hepatic transaminase concentration,
Elevated transferrin saturation,
Generalized hyperpigmentation,
Hepatomegaly,
Hypogonadism,
Impotence,
Increased circulating ferritin concentration,
Increased serum iron,
Lethargy,
Muscle weakness,
Osteoporosis,
Splenomegaly
[+]
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Mouse (8 sources):
abnormal circulating iron level,
abnormal iron level,
decreased spleen iron level,
hematopoietic system phenotype,
hemosiderosis,
increased circulating ferritin level,
increased circulating iron level,
increased susceptibility to bacterial infection induced morbidity/mortality
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.