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XB-GENEPAGE-6459813
abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| decreased length of anterior-posterior axis (10 sources), decreased size of the head (7 sources), abnormal gastrulation (6 sources), abnormal incomplete closing of the blastopore (4 sources), decreased size of the eye (4 sources), decreased size of the tail (4 sources), abnormally decreased volume of archenteron (2 sources), abnormal bending of anterior-posterior axis (1 source), abnormal development of neural tube (1 source), abnormal head morphology (1 source), abnormally delayed closure of blastopore (1 source), absent eye (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: abl2 manipulated (6 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + abl2 (10 sources), Xla Wt + abl2 MO (9 sources), Xla Wt + abl2del1 (1 source), Xla Wt + abl2del2 (1 source), Xla Wt + abl2 MO (1 source), Xla Wt + dnabl2K306R (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (8 sources): abnormal cerebral cortex pyramidal cell morphology, absent startle reflex, decreased aggression, decreased startle reflex, nervous system phenotype, novel environmental response-related retropulsion, reduced fertility, transmission ratio distortion |