| Monarch Ortholog Phenotypes
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Human (33 sources):
Abnormal dental enamel morphology,
Abnormal endocardium morphology,
Abnormal fingernail morphology,
Abnormal lip morphology,
Abnormal toenail morphology,
Abnormal vagina morphology,
Abnormality of temperature regulation,
Abnormality of the immune system,
Abnormality of the mouth,
Abnormality of the nail,
Abnormality of the orbital region,
Abnormality of the skin,
Abnormality of vision,
Broad nail,
Cheilitis,
Cough,
Dyspareunia,
Erythema,
Feeding difficulties in infancy,
Hematuria,
Hemoptysis,
Hepatitis,
Hyperkeratosis,
Onychomycosis,
Papule,
Pruritus,
Recurrent aphthous stomatitis,
Recurrent infections,
Recurrent respiratory infections,
Recurrent urinary tract infections,
Seizure,
Skin rash,
Skin ulcer
[+]
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|
Mouse (4 sources):
abnormal chemokine level,
decreased susceptibility to experimental autoimmune encephalomyelitis,
increased interleukin-17 secretion,
no abnormal phenotype detected
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.