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Summary Expression Phenotypes Gene Literature (1) GO Terms (3) Nucleotides (84) Proteins (41) Interactants (16) Wiki

cfap43     cilia and flagella associated protein 43

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
obsolete abnormal cilium motility (5 sources), abnormal locomotory behavior (1 source), abnormal swimming behavior (1 source), edematous circulatory system (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cfap43 manipulated (1 source), cfap43 assayed (3 sources)
Computed annotations: cfap43 assayed (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla + cfap43 MO (3 sources), Xla wt + cfap43 sgRNA1 CRISPR (3 sources), Xla wt + cfap43 sgRNA2 CRISPR (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (30 sources): Absent sperm flagella, Apathy, Bowel incontinence, Bradykinesia, Broad-based gait, Coiled sperm flagella, Deficit in phonologic short-term memory, Dementia, Gait disturbance, Global developmental delay, [+]
Mouse (14 sources): abnormal cauda epididymis morphology, abnormal motile cilium morphology, abnormal sperm axoneme morphology, abnormal sperm flagellum morphology, abnormal sperm head morphology, absent sperm flagellum, asthenozoospermia, coiled sperm flagellum, decreased sperm progressive motility, immotile sperm, [+]

View all ortholog results at Monarch