Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (4) GO Terms (8) Nucleotides (110) Proteins (43) Interactants (654) Wiki
XB-GENEPAGE-852702

cers2     ceramide synthase 2

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal axis elongation (1 source), abnormal gastrulation (1 source), abnormally delayed closure of blastopore (1 source), absent head (1 source), absent tail (1 source), decreased length of anterior-posterior axis (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cers2 assayed (1 source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + cers2 MO (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (8 sources): abnormal brain white matter morphology, abnormal cerebellar granule layer morphology, abnormal hippocampal fimbria morphology, abnormal lipid homeostasis, abnormal myelin sheath morphology, increased hepatocellular carcinoma incidence, increased liver tumor incidence, integument phenotype