| Monarch Ortholog Phenotypes
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Human (6 sources):
Absent hand,
Aniridia,
Finger syndactyly,
Oligodactyly,
Sensorineural hearing impairment,
Split hand
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Mouse (39 sources):
abnormal alisphenoid bone morphology,
abnormal basicranium morphology,
abnormal basisphenoid bone morphology,
abnormal brain development,
abnormal craniofacial bone morphology,
abnormal craniofacial development,
abnormal first pharyngeal arch morphology,
abnormal frontal bone morphology,
abnormal gonial bone morphology,
abnormal hindlimb morphology,
abnormal interparietal bone morphology,
abnormal mandibular angle morphology,
abnormal mandibular prominence morphology,
abnormal maxilla morphology,
abnormal middle ear ossicle morphology,
abnormal nasal bone morphology,
abnormal nasal capsule morphology,
abnormal neurocranium morphology,
abnormal palate morphology,
abnormal phalanx morphology,
abnormal pterygoid process morphology,
abnormal snout morphology,
abnormal stylohyoid ligament morphology,
abnormal temporal bone squamous part morphology,
abnormal thyroid cartilage morphology,
abnormal vibrissa morphology,
abnormal viscerocranium morphology,
abnormal zygomatic bone morphology,
absent Meckel's cartilage,
absent mandibular coronoid process,
aerophagia,
craniofacial phenotype,
decreased tympanic ring size,
lower jaw to upper jaw transformation,
neonatal lethality, complete penetrance,
open neural tube,
perinatal lethality, complete penetrance,
small mandible,
small presphenoid bone
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.