sftpd Phenotypes

Phenotypes

XB-GENEPAGE-853561

Gene Symbol: sftpd Gene Name: surfactant, pulmonary-associated protein D

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal alveolar macrophage morphology, abnormal chemokine level, abnormal cytokine level, abnormal lipid homeostasis, abnormal lung volume, abnormal macrophage physiology, abnormal pulmonary alveolus epithelium morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary elastic fiber morphology, abnormal surfactant composition, abnormal surfactant physiology, abnormal surfactant secretion, enlarged alveolar lamellar bodies, increased macrophage cell number, increased neutrophil cell number, increased susceptibility to Orthomyxoviridae infection, increased type II pneumocyte number, overexpanded pulmonary alveoli, thick pulmonary interalveolar septum [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal alveolar macrophage morphology, abnormal chemokine level, abnormal cytokine level, abnormal lipid homeostasis, abnormal lung volume, abnormal macrophage physiology, abnormal pulmonary alveolus epithelium morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary elastic fiber morphology, abnormal surfactant composition, [+]