Monarch Ortholog Phenotypes
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Human (13 sources):
Abnormal Descemet membrane morphology,
Abnormal corneal endothelium morphology,
Anterior synechiae of the anterior chamber,
Band keratopathy,
Corneal opacity,
Ectopia pupillae,
Epiphora,
Glaucoma,
Iris atrophy,
Photophobia,
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Mouse (44 sources):
abnormal angiogenesis,
abnormal aortic sac morphology,
abnormal cephalic neural fold morphology,
abnormal digestive system development,
abnormal dorsal-ventral axis patterning,
abnormal embryo turning,
abnormal embryonic neuroepithelium morphology,
abnormal embryonic tissue morphology,
abnormal endocardium morphology,
abnormal extraembryonic tissue morphology,
abnormal forebrain development,
abnormal foregut morphology,
abnormal head mesenchyme morphology,
abnormal heart development,
abnormal heart looping,
abnormal heart tube morphology,
abnormal hindgut morphology,
abnormal neural crest cell delamination,
abnormal notochord morphology,
abnormal optic eminence morphology,
abnormal optic pit morphology,
abnormal placenta vasculature,
abnormal placental labyrinth vasculature morphology,
abnormal prechordal plate morphology,
abnormal surface ectoderm morphology,
abnormal vasculogenesis,
abnormal vitelline vascular remodeling,
abnormal vitelline vasculature morphology,
absent intersomitic vessels,
absent myocardial trabeculae,
absent otic pit,
absent pharyngeal arches,
absent vitelline blood vessels,
cardia bifida,
decreased embryo size,
decreased embryonic neuroepithelial cell proliferation,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
incomplete rostral neuropore closure,
increased embryonic neuroepithelium thickness,
increased neural crest cell apoptosis,
open neural tube,
small heart,
small pharyngeal arch
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View all ortholog results at Monarch
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