| Monarch Ortholog Phenotypes
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Human (1 source):
Seizure
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Mouse (36 sources):
abnormal associative learning,
abnormal behavioral response to nicotine,
abnormal brain wave pattern,
abnormal epididymis morphology,
abnormal eye electrophysiology,
abnormal habituation to a new environment,
abnormal lateral geniculate nucleus morphology,
abnormal nicotine-mediated receptor currents,
abnormal pulmonary ventilation,
abnormal response to new environment,
abnormal response to novelty,
abnormal social investigation,
abnormal superior colliculus morphology,
abnormal tidal volume,
behavior/neurological phenotype,
decreased anxiety-related response,
decreased chemically-elicited antinociception,
decreased erythroblast number,
decreased susceptibility to injury,
decreased visual acuity,
enhanced coordination,
enhanced spatial learning,
fragmentation of sleep/wake states,
homeostasis/metabolism phenotype,
immune system phenotype,
impaired passive avoidance behavior,
increased B cell proliferation,
increased pulmonary ventilation,
increased susceptibility to induction of seizure by inducing agent,
increased tidal volume,
myeloid hyperplasia,
no abnormal phenotype detected,
premature death,
preweaning lethality, incomplete penetrance,
respiratory system phenotype,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.