rif1 Phenotypes

XB-GENEPAGE-920161

Gene Symbol: rif1 Gene Name: replication timing regulatory factor 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: rif1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (18 sources): abnormal class switch recombination, abnormal double-strand DNA break repair, abnormal epigenetic regulation of gene expression, abnormal mitosis, decreased cell proliferation, decreased IgG1 level, decreased IgG2b level, decreased IgG3 level, embryonic growth retardation, embryonic lethality, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, immune system phenotype, increased cellular sensitivity to ionizing radiation, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, preweaning lethality, incomplete penetrance, reduced fertility [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (18 sources): abnormal class switch recombination, abnormal double-strand DNA break repair, abnormal epigenetic regulation of gene expression, abnormal mitosis, decreased cell proliferation, decreased IgG1 level, decreased IgG2b level, decreased IgG3 level, embryonic growth retardation, embryonic lethality, complete penetrance, [+]