| Monarch Ortholog Phenotypes
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Human (2 sources):
Abnormality of refraction,
Myopia
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Mouse (33 sources):
abnormal cone electrophysiology,
abnormal eye electrophysiology,
abnormal learning/memory/conditioning,
abnormal motor capabilities/coordination/movement,
abnormal retina cone cell morphology,
abnormal retina development,
abnormal retina ganglion cell morphology,
abnormal retina ganglion layer morphology,
abnormal retina inner plexiform layer morphology,
abnormal rod electrophysiology,
abnormal sexual interaction,
absent amacrine cells,
absent photoreceptor inner segment,
absent photoreceptor outer segment,
absent retina horizontal cells,
absent retina rod cells,
behavior/neurological phenotype,
decreased aggression,
decreased body size,
decreased exploration in new environment,
decreased retina inner nuclear layer thickness,
decreased retina rod cell number,
disorganized retina layers,
disorganized retina outer plexiform layer,
hearing/vestibular/ear phenotype,
impaired limb coordination,
increased retina cone cell number,
increased retina ganglion cell number,
limb grasping,
nervous system phenotype,
no abnormal phenotype detected,
retina photoreceptor degeneration,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.